MIRACLE

The MIRACLE project requires inputs from molecular biology, biosensor, micro- and nano- technology, microfluidics as well as from system integration technology for the successful achievement of its challenging objectives. The execution of the different tasks will be carried out in parallel. It is important to note that the proposed microsystem is a generic platform using breast and prostate cancer as model system that will be demonstrated within the MIRACLE IP, but the proposed technological platform has immense application in, for example, the fields of pathogen detection, stem cell isolation as well as foetal cell isolation from maternal plasma .

As the different tasks are largely multidisciplinary, comprising both technological and biological input, the approach taken will result in the necessary cross-fertilisation between the different disciplines. Both the individual modules, as well as the integrated platform will be compared to their classical counterparts and will be evaluated using clinical samples. To achieve the challenging goals within MIRACLE, the total workload is divided into 10 work packages (see below).